The 10 Best Bed Bug Killer Sprays Comparison Review [UPDATED 2019] Buyer's Guide

Best Bed Bug Killer Sprays: photo
Author: Michael Potter

Updated 11-06-2019

Bed bugs have become a common household problem since the World War II era. Around that time they were eliminated with loads of different pesticides. However due to their undercover behavior and habits combined with a lack of public awareness, their infestation spread at a very rapid rate world-wide. Spray is the fastest killer. But which one to choose? We'll help you to make the right choice. Here you'll find 10 best bed bug sprays: natural and professional insect killers.

Table of Contents:

Even today no specialist can identify for sure what actually causes an increased bed bug activity globally. What has been proven is that they have been primarily identified in the hotel rooms. That is why this specific insect is generally associated with travelling, but not with poor sanitation or just poverty. Yes, cleanliness and social status have nothing in common with getting these bloodsuckers. This misconception leads to the million dollar question of how to get rid of bed bugs in the hotels, commercial buildings, public transportation, and people’s houses.

Are bed bug sprays effective?

The truth is that none of the methods alone would eliminate all the bed bug infestation. You’ll need to use several techniques for the control to be effective. This approach includes the prevention, monitoring, and use of chemical pesticides. Bed bug sprays will be one of the effective treatment methods that you need to employ along with any other technique of your choice (vacuuming, fumigation, etc).

Without residual pesticide application bugs can travel freely and safely. They just move from the luggage right into your bed, and thus a new infestation begins. Luckily, today’s pest management practices can boast of a miraculous elimination of bed bugs. The infestation in the hotels and motels, as well as apartments and houses today can be eliminated with the help of pesticides.

But as VDACS research shows, “There are relatively few insecticide products registered for indoor use. Those that are registered are primarily from one chemical class, the pyrethroids. Bed bug populations in the United States are known to be resistant to pyrethroids, therefore no single insecticide is capable of eliminating a bed bug infestation if used alone”. Scientists recommend not relying entirely on the repellents and IGRs (insect growth regulators) in terms of completely exterminating bugs, but use such products as liquid insecticides, insecticidal dusts and aerosol insecticide sprays.


Top Bed Bug Killer Sprays: photo

Top-10 Best Bed Bug Sprays

We have included 10 best killer sprays in our today’s review. There are both artificial chemical and organic products. Each product is great in its own way, so instead of rating them, we’ll give you a more detailed description of each of them so that you could choose one that suits your needs the best.

Bed Bug Killer by EcoRaider, 100% Fast Kill and Extended Protection, Green & Non-toxic

Bed Bug Killer by EcoRaider: photo

This 16 oz bottle is #1 Best Seller in Pest Control Sprayers. Among the active ingredients of EcoRaider Spray are geraniol (1%), cedar extract (1%) and Sodium Lauryl Sulfate (2%). The manufacturer claims that it is the most effective spray, as the Entomological Society of America Journal Publication named it "the only natural product that kills bed bugs with 100% efficacy".  The EcoRaider is available as a travel size spray (Check current price) and a 1 gallon jug (Check current price).

The scientists consider two oil-based products (based on the Rutgers University study) to be “surprisingly effective against adult species and eggs, ... and potentially useful pesticide for controlling bed bug infestations”. They are EcoRaider™ (Geraniol & Cedar extract) and Bed Bug Patrol™. Direct spraying of EcoRaider™ caused 100 percent mortality after 10 days. 

In summary, it destroys any kind of bed bugs (even those resistant to insecticides); kills adults, larvae, and even causes high mortality (86%) in bugs at the toughest egg stage. What do users say about the effectiveness of the product? Many of them agree that the sprays, including this one, are most effective as part of an integrated approach - together with the use of a mattress cover and traps. By the way, some users have tried to improve the deadly effect of this spray, mixing it with Gentrol Insect Growth Regulator - and stated that this mix has worked better. You can also read more than 2000 other reviews and find out more helpful tips.

Bed Bug Killer by EcoRaider
Bed Bug Killer by EcoRaider

The Entomological Society of America Journal Publication named it the only natural product that kills bed bugs with 100% efficacy.

And finally, the other characteristics of the product. Cedar scent is not for everyone, but it is quite tolerant: "The smell of this spray is intense, it smells like concentrated cedar, like a cedar chest, but once it dissipates, the smell is not too bad". Also, Eco Raider does not leave marks on the furniture or floor, so you can use it anywhere without getting spots and stains.

EcoRaider: 16 oz bottle: Check the current price

2 oz travel size bottle: Check the current price

1 gallon jug: Check the current price

Low toxicity contact sprays SteriFab™ and Bedlam® for treating bed mattresses

Steri fab2bedlam2

Yet another two products recommended by the entomologists. As with the other contact sprays, these would kill the bed bugs on contact, and would become inefficient as soon as they dry out. Also, they would have no effect whatsoever on bed bugs' eggs. Because of the low toxicity levels, both SteriFab and Bedlam can be used on mattresses, furniture, and other places that are most habituated by humans (and pets) in the house.

In case you’d want to cover larger area, we’d advise to go for SteriFab kit, which includes one gallon of Sterifab spray and one pint of bactericide, both of which are pretty potent sanitizers and would work on various kinds of pests, including primarily bed bugs. The seller provides the following recommendations for use on mattresses: use 4-5 ounces of Sterifab for single bed and folding cot mattresses and 6-8 ounces for double bed.

In case you’re looking for a smaller and more portable version and your bed bug infestation is not as big, then consider purchasing low toxicity Bedlam Insecticide Spray or Bedlum Plus Aerosol. And although we’ve stated that Bedlam contact spray is not efficient against eggs, the Bedlam Plus is a residual spray, that’s much more potent at killing bed bugs, and is pretty efficient at eliminating pyrethroid-resistant bed bugs with their eggs for two weeks after treatment. It can be still, however, used on clothing, although it’s more toxic than a contact spray. Bedlam Insecticide Spray is a contact spray that works just as SteriFab.

Professional pesticide | Temprid SC Killer

Temprid SC Bed Bug Killer: photoTemprid SC is a professional dual action pesticide. It can kill over 50 types of pests including bed bugs. Its active ingredients are two powerful insecticides: beta-cyfluthrin and imidacloprid. The former kills regular species while the latter will be able to deal with pyrethroid-resistant ones. The killer is available both as a ready-to-use spray and a concentrated suspension that has to be dissolved in water. Concentrate is better-suited for a large-scale invasion while a spray is more appropriate for smaller areas.

The manufacturer doesn’t recommend spraying Temprid directly on surfaces where people are constantly in contact (cushioned furniture, mattresses). Use it for treating joints, seams and edges of the mattresses, as well as box springs, bed backs, any furniture and floor cracks, corners, skirting boards, carpets, shelves, cabinets and curtains.

95% of users are satisfied with the concentrate’s killing effect as it has received a high rating. They have additionally learned from the manufacturer that Temprid’s effect is best if used immediately after being dissolved without leaving it idle for a long time. As for the spray, it should be used during a small-scale invasion. Judging by the customers’ reviews, 2-3 applications are enough to get rid of bed bugs completely.

Temprid, Spray:  Check the current price

Temprid Sc, concentrated insecticide: Check the current price 

Harris Bed Bug Killer

Harris Bed Bug Killer & Harris Toughest: photoHarris with deltamethrin kills bed bugs and lice on contact; the customers therefore call it “instant death” and often use it simultaneously with Harris Bed Bug Diatomaceous Earth Powder (Check current price).

One of the customers has shared that it were their kids who brought bed bugs home and that for the first couple of months these insects went completely unnoticed as they were breeding actively and hiding well. Their activity peaks at night, when humans are asleep. Harris Killer helped reduce the population in few weeks. Harris also has 1 Gallon Toughest Bed Bug Killer for  "pyrethroid resistant" bed bugs and eggs (Check current price).

Some consumers tested this product on cockroaches. Others use it as a preventive measure. In fact, another reason for us to really like this spray is that it comes in large volume and that it is really cost-saving (which experienced users appreciate the most). You can read all customer reviews as a proof.

Harris Bed Bug Killer  Check the current price

Harris Toughest (for "pyrethroid resistant" bed bugs):  Check the current price 

Bed Bug Egg Killer Sprays | Harris | Ortho

Bed Bug Egg Killer Sprays: photo

For spot treatment use aerosol sprays. High pressure helps to treat deep into cracks and crevices where bed bugs are hiding. It is good for treatment on and around bed frames, headboards, walls, bedding, box springs, luggage, drapes and other window appointments. Customers admit that the bugs die within 3 seconds after coming into contact with the spray. But don't stop. Re-spray all of the surfaces weekly until no signs of bed bugs are to be seen.

The manufacturers assure that these bottle’s contents are able to kill not only regular bed bugs, their eggs, fleas, ticks and lice, but also pyrethroid-resistant species. When we looked into this issue in more detail, we found a National Geographic article claiming that certain types of bed bugs have become pyrethroid insecticide-resistant, and humans are to blame as they’ve been exterminating these insects like that for ages. This resulted in DNA mutation and appearance of chemical-resistant genes.

Harris is EPA Registered - Approved for use in homes with people and pets by the Environmental Protection Agency (No. 1021-1767-3).

Ortho: Check the current price

Harris:  Check the current price

Bed Bug Killer Patrol

Natural Bed Bug Killer Patrol: photoNatural plant extracts of peppermint and clove oils and Sodium Lauryl Sulphate from сoconut extract are among the active ingredients of this non-toxic spray. The product promises to kill bed bugs on contact. Its residual effectiveness under lab conditions has been proven by the Rutgers University scientists. They claim that although it takes longer time to kill on contact than chemical sprays, 91-92% mortality rate was detected within 10 days after treatment.

It is also reported that this spray can be applied not only on these bloodsuckers’ regular home hideouts, but also directly on the mattress and its cover, cushioned furniture and other surfaces with which people come in contact. The users’ opinions on its effectiveness are contradictory. Some find it helpful like no other treatment, while others note the slowness of its killing action (“Yes, it seems it does work ok but only on direct contact with the bed bug that it dies and not all that fast like 15 minutes or more.”) and lack of residual effect (“This stuff will work on live bugs if it is sprayed directly on them. Once it has dried, worthless,”). It is up to you to make the right choice, so read all customer reviews to learn more.

Bed Bug Killer Patrol:  Check the current price

Bed Bug Killer By Eco Defense - All Natural Organic Formula 

Bed Bug Killer By Eco Defense: photo

In spite of the fact that the manufacturer claims that it is all natural, we can’t consider it to be fully organic as it contains, for example, such synthetic chemical as sodium lauryl sulfate (SLS). The active component is Geranium Oil. Inactive ingredients: Distilled Water, Citric Acid, and Ethyl Lactante. It is a good thing that some of the active components are natural ones, but nevertheless we can’t call it all-natural.

The manufacturer promises that the Eco Defense Spray will kill bed bugs once it comes in contact with them, as soon as possible, won’t leave any stains or artificial odor, but is this really so? Yes, some users speak of “killer results” in their reviews. Others share that it didn’t work at all or simply paralyzed the insects. The lack of odor is also debatable as some customers don’t complain of it, while others say that the odor is worse than chemical sprays’ one. You might as well read all of the customer reviews on your own and make your own judgment. As for us, we advise using it combined with other treatments as a means of indemnifying.

Eco Defense:  Check the current price

Bed Bug Killer Sprays Comparison Chart

Product Active Ingredients Odor

EcoRaider (16 oz)

Bed Bug Killer by EcoRaider: photo

Geraniol, Cedar extract, Sodium Lauryl Sulfate

Cedar scent is not for everyone, but it is quite tolerant.

EcoRaider Travel/Personal Size (2 oz)

Bed Bug Killer by EcoRaider Travel: photo

Geraniol, Cedar extract, Sodium Lauryl Sulfate Cedar scent is not for everyone, but it is quite tolerant.

EcoRaider (1 Gallon Jug)

EcoRaider Bed Bug Killer Spray 1 Gallon Jug: photo

Geraniol, Cedar extract, Sodium Lauryl Sulfate Cedar scent is not for everyone, but it is quite tolerant.



Low odor

Temprid Sc Insecticide



Low odor



It is odorless. 

Harris Toughest

Phenothrin, Imidacloprid Slight chemical smell

Chapin Sprayer

Chapin Sprayer: photo


 –  –

Ortho Home Defense

Phenothrin, Imidacloprid  It is odorless. 

Harris Aerosol Spray

Phenoxybenzyl, Dimethyl, N-Octyl-bicycloheptene dicarboximide

It is odorless.

Bed Bug Killer Patrol

Natural plant extracts of peppermint and clove oils, Sodium Lauryl Sulphate Low odor

Steri-fab Bed Bug Spray

Fungicide, mildewcide, germicide, viricide  – 

Bedlam Insecticide Spray

Phenoxybenzyl, dimethyl, cyclopropanecarboxylate, N-Octyl bicycloheptene dicarboximide Low odor 

Eco Defense

Sodium Lauryl Sulfate, Geranium Oil Some customers don’t complain of it, while others say that the odor is worse than chemical sprays’ one.

*Although many users spray these products right over their sheets, we wouldn’t recommend doing it if the said product contains sodium lauryl sulfate (SLS), a synthetic chemical which is also present in all other cleaning products. According to the United States Department of Agriculture, in spite of the fact that SLS is commonly used in household chemicals production and other products, long-term contact with this substance can lead to dermatitis.

If you’re still torn between a spray and a fogger, follow the specialists’ advice. According to the National Center for Healthy Housing"Bug bombs" are not effective against bed bugs. The pesticide droplets generated by foggers typically do not penetrate the hiding spaces used by insects.

As for us, once again we would like to remind you (along with the University of California professors), that Insecticides must be combined with infestation prevention measures, such as removing and cleaning infested beds, bedding, and other harborage sites, as well as nonchemical tactics such as steam or heat delivery.

How It Works: The Scientists’ Opinions on Bed Bug Killer Sprays Effectiveness

What scientists unanimously agree on is that homemade bed bug sprays are a far greater threat than commercial ones. Do not use them! Any sprays containing detergents as well as alcohol, are dangerous. Commercial products, on the other hand, have undergone the necessary laboratory tests and are allowed for indoor use. The Michigan State University experts recommend using only “EPA- and MDARD-registered products that come in their original packaging”.

Don’t count on repellents either, as the Department of Entomology, Virginia Tech states: “However, none of our current insecticide products appear to be repellent to bed bugs, particularly after they have dried. For whatever reason, bed bugs do not recognize repellent chemicals the way that other household insects do. So far, no insect repellent or insecticide product has been able to stop bed bugs from biting.”

That is why we will have to resort to contact killing with natural and artificial chemical insecticides. Let’s see what the entomologists recommend doing and how.

Natural Bed Bug Sprays

Some conditionally organic low-toxic sprays can indeed kill bed bugs on contact. As the Texas A&M AgriLife Extension unit specialists state, don’t expect any residual action after such sprays are dry. In addition, it has been proven that these pests can avoid any places treated with organic sprays. Along with that, the scientists consider two oil-based products (based on the Rutgers University study) to be “surprisingly effective against adult species and eggs.”  They are EcoRaider ™ (Geraniol & Cedar extract) and Bed Bug Patrol ™. Direct spraying of EcoRaider™ causes high initial death toll (80%) and 100% of the insects were dead within 10 days.

How Bed Bug Spray Works

Nowadays, pyrethrin- or pyrethroid-based (the latter are synthetic analogues of pyrethrins) remain the most popular chemical sprays. They attack nerve cells and cause multiple nerve excitation. This ultimately leads to paralysis and the death of the insects. These pesticides are one of the most powerful ones, but many insects have become resistant to them over the years. Nevertheless, pyrethroid-based sprays are most common today.

According to the United States Environmental Protection Agency (EPA), the registered active ingredients for bed bug control include 16 pyrethrins and pyrethroids, 4 neonicotinoids, 3 inorganic compounds, chlorfenapyr, DDVP (dichlorvos), propoxur, S-hydroprene, alcohol, and neem oil.

The University of Kentucky Entomology team also considers professional products such as Temprid ® SC, Transport® and Phantom® effective. Among their active ingredients, not only pyrethroids are found, but also neonicotinoid compounds (imidacloprid, acetamiprid) as well as pro-insecticide chlorfenapyr.

All these products are reviewed in our Top-10 best killer sprays. Read it to learn more.

Are sprays better and more effective than other methods (vacuuming, bombs (foggers), traps, dusts&powders)?

There’s no simple answer to that question. According to the US FTC, bed bugs have developed a resistance to chemicals that are used in common pesticides, bug bombs, and foggers. Also, according to the Texas A&M AgriLife Extension, fumigation is not very effective: bed bugs almost always hide in crevices where fogger aerosols do not penetrate. Vacuuming can be ineffective because while it can suck up a lot of insects, eggs are much harder to get. Besides, bed bugs can relocate to other rooms when you’ll try to empty the vacuum canister. So, all of the methods have their limitations, and you’ll have to use several for the extermination to be truly effective.

How long does bed bug spray last?

There are two types of bed bug sprays that are available on the market, namely contact and residual sprays. The time it takes to kill a bug will essentially depend on which type you use in your household.

Contact vs Residual Sprays

If you choose to use contact sprays then they will almost immediately kill the bug upon contact, whereas if you happen to buy a residual spray it will work slowly but will also last longer. Another thing that you have to consider before buying is what type of chemical formula the spray has. You need to ensure you’re buying the latest version of the spray with the newest chemical compounds because bugs have developed resistance to old sprays and you’ll just waste your money on something that would be totally ineffective.

The EPA website has a tool to help you choose the latest best pesticide for your particular situation. For example, pyrethrins and pyrethroids are the oldest known compounds, that might prove to be ineffective when used alone. So, look for insecticides that would combine both pyrethrin and any another chemical class. Otherwise, go for desiccants that work physically through destroying the outer coating of a bed bug, meaning bed bugs cannot develop resistance to them.

How long does it take to eliminate all bed bugs using sprays?

Contact sprays will kill affected bed bugs immediately, while residual sprays will require more time (several minutes) to kill but will also last longer, sometimes even up to a year after application. The time it would take to eliminate a bed bug infestation depends on the size of that infestation, other methods you are going to use, type of spray, and other individual factors.

IGR products

The Department of Entomology, Virginia Tech specialists explain that today “there is only one insect growth regulator that is labeled for bed bug control – hydroprene”. However, some latest research has shown that IGRs don’t actually sterilize these insects, they slowly kill them instead. This means that bed bugs can produce at least one generation of offspring before dying. The Cornell University experts don’t recommend rely on IGRs too much either (“Insect Growth Regulators (IGRs) affect the development and reproduction of insects. Although they can work well, they don’t kill bugs quickly”). Therefore, we can say that you’d better use IGRs that are complementary to other insecticides.

Why Are Insecticides More Effective Than Natural Products?

Professional products are most recommended for use by experts. Their advantage is their long-term action and residual killing effect after they are dry. However, in order for an adult insect to die of an insecticide’s residual effect, it should remain within the boundaries of the treated territory for several days. For this reason, it’s best to spray chemicals in places where insects typically hide, such as floor cracks, corners, places along and under the skirting boards.

Also remember that these pests’ eggs are most difficult to eliminate as their outer shell protects future larvae from insecticides. That is why several repeat treatments will be necessary to remove any larvae that could hatch.

  How Bed Bug Killing Sprays Work


Active Ingredients

Killing Action

Residual Action

Natural contact sprays

Geranium oil, geraniol, clove oil, sodium lauryl sulfate etc

Are partially effective on contact.


Artificial chemical contact sprays

Pyrethrins and pyrethroids

Kill on contact, may be ineffective against certain pyrethroid-resistant populations.

High level of residual control: kill several days after drying.

Neonicotinoids (imidacloprid, acetamiprid), chlorfenapyr and other chemicals

Kill on contact, no insect resistance has been determined.

High level of residual control: kill several days after drying.



Poison the insects on contact, death will come before sterilization.

High level of residual control: kill several days after drying.

What You Should Know Before Spraying the Room

All sprays work in the same way: they kill the insects once they come in contact with them. The manufacturers promise that this is a matter of minutes or even seconds and the killing effect will last for a few hours following the application.

How long should you use spray

The experience reveals that it’s better to use the spray few times regardless of the infestation scale instead of counting on the effect of a single use. In addition, the first spray can simply paralyze the insects rather than directly kill them.

Never go for a single measure even if it seems that the bed bugs are gone. University of California scientists advise to combine the insecticides with infestation prevention measures, such as removing and cleaning infested beds, mattresses, and other harborage sites, as well as nonchemical tactics such as steam or heat delivery. Make sure you also invest in a mattress cover.

Where to apply bed bug spray

Know the dangerous spots and objects in the room to be sprayed, such as:

  • Luggage you’ve brought from a trip. As we’ve mentioned earlier, bed bugs tend to travel and come back home with you and then spread and breed all over the house
  • Floor and walls, carpets, cracks in the wooden floor, in the corners, door and window frames, behind the paintings or wallpaper, outlets.
  • Furniture and your sleeping place, the drawers in the chest or cabinets, sofa and armchair upholstery, mattresses, pillows, bed sheets and others.

where do bed bugs live: photo

Monitoring devices such as ClimbUp® are useful for confirming the presence of bed bugs when a visual inspection cannot. When installed under bed legs, such traps provide a barrier between floor and your sleeping place what can potentially reduce bites, especially when beds are pulled slightly away walls and encased, as per advice of Michael F. Potter, Extension Entomologist, University of Kentucky.

How to apply bed bug spray on carpet

You would apply the spray on the carpet, just like anywhere else, really: spray it evenly along the edges first, then underneath the carpet. I would suggest spraying across all carpeted area to ensure not a single bug would escape its fate.

How to spray bed bug spray on a mattress

First off, inspect the mattress carefully and size up the extent of the infestation. If there are a lot of holes and feces spread across the mattress area, then you’d better be off without this mattress, really, throw the stuff right into the dumpster. If you are not ready to part with your mattress, then inspect the folds and seams of your mattress, the head and footboards, then vacuum your mattress throughly.

After that, apply the spray along these seams and stitches, head and footboards that you’ve previously inspected. Leave the spray to fully dry and only then continue to use your mattress. I’d recommend using bed bug proof mattress encasements that are placed over the mattress to protect it from damage that seldom comes from bed bugs.

Which one to choose?

Here we’ll review some of the common situations where you’d require the use of a bed bug spray and my recommendations as to which one you’d better buy.

 Bed bug spray for clothes/fabric

Always check the label to make sure it can be used on fabric or furniture. I’d advise trying natural sprays first, like Eco Defense Bed Bug Killer or EcoRaider Bed Bug Killer. And if that doesn’t work, go the hard way and purchase something that’s rich in deadly chemicals, like Temprid Ready Spray, that should do the trick.  

 Bed bug spray for bed/mattresses

Any bed bug spray that can be used on fabric is good for mattresses too. If you want something for a change, then consider good-old Harris Bed Bug Killer, that’s way too good not to recommend. It will deal with any pyrethroid resistant blood sucker, so don’t you worry.

 Bed bug spray for travel/suitcases/luggage

In case you want to be bed bug-free at all times, I’d recommed carrying something lightweight, like Bed Bug Rid Pest Spray, which is conveniently sold in bottles of 2 oz. Thus, it won’t be a burden for you to carry it around. Otherwise, if you want something more reliable and chemical, then good old Harris (16 oz) is your best bet.

 Bed bug spray for body/skin

Well, there is no such thing as a safe bed bug spray for skin in the entire universe. If any of those chemicals are absorbed through the skin, you are in trouble and might need medical attention immediately.

 Bed bug spray for cars

In case your bed bugs have reached your car, then it might be a good idea for hiring a professional and see if what you have are really bed bugs and not any other type of pest.  Because what might be effective against bed bugs can be totally useless for other pests. Anyway, if you’re pretty sure your car is reeking with bed bugs, then all sprays that are good for furniture will also be okay for a car. In case you need specific recommendations, then try classic J T Eaton Bug Killer

 Bed bug spray for house

If your whole house is infested, then go for a huge spray canister or a concentrate, both of which won’t break your family budget. Consider buying Harris Bed Bug Killer 1-gallon canister ,  Tempo Ultra Bottle Concentrate or Tempo Contact Insecticide Bottle.

 Bed bug spray for hotels

If you happen to check into a hotel room with bed bugs, either leave the hotel immediately or ask the reception to change your room. If you’re a hotel owner, then you’d better hire a professional exterminator or pest control company that would deal with the infestation in a timely fashion since it’s your money and reputation that’s at risk here not only the health of your guests.

 Bed bug spray for pets

Save your pooch by taking him to the vet, please. If that’s not option (although that’s always an option), try the following products: Bed Bug Killer from Bugstrap (all natural formula) or chemical J T Eaton for Dogs

 Bed bug spray for furniture

The sprays that we’ve covered for clothes and mattresses can be used safely for any other furniture. Steri-Fab Bed Bug Kit is a good value for money in case you need to apply the spray to a larger area and a lot of items in your house.

How to use a bed bug spray: RULES & precautions

Bed bug sprays can come in different form factors, like liquid, spray, or concentrate. Liquid type usually includes contact sprays that kill bugs instantly upon contact. Residual aerosols kill bugs over time. And concentrates need to be diluted with water and are used to cover larger areas.

Irrespectively of which one you’re going to choose, always read a product label carefully and follow the instructions outlined by the manufacturer. 

Now, let’s look at how to use sprays of different form factors.

If you choose to use the liquid contact spray (like Steri-Fab):

  • Shake the bottle well to ensure the chemicals inside are agitated and ready to shoot
  • Squirt the spray evenly by pulling the trigger along the crevices, cracks, jambs, corners of a room that you want to treat, including headboards, floorboards, and the like
  • Continue to spray until all affected areas are treated and evenly coated with the spray
  • Leave the spray to dry before touching any of the areas that you’ve treated
  • Unlike some residual aerosols, contact sprays can be applied to upholstered surfaces, like sofas, and mattresses.

In case you opt for an aerosol spray (like Bedlum Plus):

  • Shake it up before spraying
  • Hold the spray nozzle and evenly apply along the crevices, cracks, and the like
  • Unlike liquid sprays, there are certain restrictions on where you can apply aerosols. Some can be still used on furniture, whereas many others cannot (always check the label to see where you can use it)

If you use concentrate spray liquid (like Syngenta Insecticide):

  • Read the label carefully to see how the mixture needs to be prepared
  • Take an empty spray bottle and fill it with a portion of a concentrated liquid required by the label and instructions, dilute it with water, and shake the resulting solution thoroughly
  • Once the mixture is set up, pull the trigger intermittently and evenly apply the spray across all crevices and cracks you can find


Check if the pesticide that you intend to use is registered with the EPA. If you purchase something that has not been professionally approved, it can be much more dangerous than the bed bugs themselves. Some of the things that are illegal to use against bed bugs include diatomaceous earth not registered with the EPA; carbon dioxide, propane, and helium bug bombs.

A few of other “DON’Ts”:

  • Do not use outdoor pesticides indoors
  • Do not buy pesticides from street vendors or other unreliable sources
  • Do not apply any of the pesticides on your skin
  • Do not apply pesticides to furniture or bedding UNLESS allowed on a label

There’s also such a thing as insecticide poisioning, and we thought you should be aware of this as well. This type of poisoning can happen when you inhale too much of an insecticide, accidentally swallow it, or put it on your skin. The common symptoms include difficulty breathing, heart problems, or other allergic reactions. Pyrethrins are not usually dangerous since they are derived from flowers.

Pro & Cons


  • When used in accordance with the instructions on the label and in combination with other methods, bed bug sprays can be very effective at eliminating bed bug infestation
  • They are generally safe (if approved by the EPA and used properly)


  • Might be ineffective if used alone
  • Bed bugs can develop resistance to it
  • Can be dangerous if used excessively or inappropriately

Need to hire an exterminator? Find the best licensed professionals in your area.

Reviewed by: Nissem Abdeljelil
VOTES: 47        HITS: 738359
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LoraT  •  Monday, 30 July 2018 17:38
My husband and I decided to make an unforgettable vacation, and decided to take tickets for a cruise liner. Everything went according to plan, I took with me a spray from mosquitoes, for sunburn, and bed bug killer, just in case, and I did not lose. From the very first days we felt some bites on our feet, then red spots began to appear. I immediately realized that it was bed bugs. This is an unforgettable vacation for us ......
Eren  •  Monday, 19 February 2018 11:33

I read the saybyebugs reviews and realized that it’s the perfect option for getting rid of bed bugs. First, their price is neither too high nor too low which makes it perfect. Second, judging by the reviews it is effective and gives almost a 100% result. Obviously, this is the best treatment on the market today.

NaugkNM  •  Friday, 16 February 2018 21:23

I only use the proven proof bed bug spray by Ecoraider. It is the only product that I could find allowing fully removing them. I am so happy with it that I’m going to buy a few more and use them preventively.

GangVang  •  Wednesday, 14 February 2018 10:04

I am a college student and we had a bed bug apocalypse in our dorm. I almost went nuts when an exterminator told me that treating the room will cost $1000-3000. I thought, screw this, and decided to try ecoraider bed bug killer. After a couple of days I started treating my room and bed with this spray. So far I live almost five months without these bloodsuckers’ bites. Don’t believe these exterminator corporations; you can get rid of bed bugs by yourself!

User92  •  Friday, 20 April 2018 19:26
I 'll try to use Ecorider. How long did it take you to get rid of the bedbugs?
Qopppi  •  Wednesday, 15 November 2017 19:42

It works greatly. I bought it for my mom who lives in a bloodsucker-infested house in NY. She killed a few creatures already. After spraying the ecoraider bed bug spray, the bugs are gone and never returned. After she tested this spray, I bought some more for her just in case for her to treat the rooms and to remove these ugly insects for sure.

LislysMioLlL  •  Thursday, 12 October 2017 12:28

There were quite a few bed bugs on our sofa and they left their waste too. We took the sofa outside overnight and treated it with harris bed bug spray. We put all the pillows in laundry and used the spray to treat the carpet, skirting boards and everything that was touched by the sofa. You could feel the spray’s smell, but it’s not very strong and it ventilates in a couple of hours. The product is tried and tested.

GearS  •  Thursday, 28 September 2017 16:12

We’ve been battling these nasty blood-suckers for over a year and all of the methods that we’ve tried were in vain. We bought the Harris bed bug killer as a last resort before spending five grand on exterminators. This product’s rating was quite high and we saw signification activity and population reduction within two weeks after use. But they weren’t completely removed, so we continued treating our territory. Surpassingly, we removed all of the bed bugs within a month.

KAte  •  Wednesday, 23 November 2016 22:04

I’ve been able to instantly find a perfect remedy, I use Harris bed bug killer only and I love it! I don’t see a point in replacing it with something else. It is odorless and can be used at home with kids and pets.

One  •  Wednesday, 26 October 2016 13:38

When it comes to bed bug killers, I immediately think of sprays. For better effect, apply the killer directly on live bed bugs. They are hard to notice, because they hide in daytime, but if you see them, spray them to death! It is also very good that many sprays have a lasting residual effect.

Kevin21  •  Tuesday, 18 October 2016 23:58

Hmm tell me what agent for bedbugs is better to take - natural or a pyrethroid-based one?

author  •  Saturday, 22 October 2016 13:33

Each of them has its pros and cons. Chemicals have traditionally been considered a more powerful method, but they are toxic and have restrictions. Besides, as mentioned in this article, some bed bugs may be resistant to pyrethroids. Natural sprays can show worse results and should be used for a longer period of time to achieve a permanent effect, but they are safer and you can spray them anywhere. Therefore, it’s up to you to decide which bed bugs spray to choose...

Kev  •  Tuesday, 01 November 2016 09:01

OK...Can a natural bed bug killer spray be sprayed on bed linen?

Fred  •  Monday, 07 November 2016 01:01

Yes, many manufacturers of non-toxic sprays allow such use, but don't overdo it - especially if you have sensitive skin. Many natural bed bug sprays have a chemical component SLS (Sodium Lauryl Sulfate), which, according to scientific studies, in some particular cases may cause dermatitis!

anonimus  •  Wednesday, 31 August 2016 12:05

What do you think is more effective: a spray or a bed bug powder? Are there any major differences between these two types of products?

Guest  •  Friday, 02 September 2016 19:12

I think it’s not about the killing product type (i.e. dust or bed bugs spray). The result will be the same if the product is of high quality. Go for whatever is more convenient for you. I’m used to sprays so I always buy them.

Luci  •  Thursday, 18 August 2016 09:40

Once I bought a bed bug spray that had such a peculiar and terrible smell that I couldn’t even finish the bottle. After that, I didn’t dare use such sprays at all, until my husband bought spray by Killer Green, its main advantage is that it’s completely odorless and seems to be effective against ticks.

Player  •  Wednesday, 24 August 2016 15:26

Wow, I also use it, and it’s the best bug spray for me. Before, I used to try getting rid of ticks with traditional methods, such as boric acid, but it wasn’t worth it because it didn’t kill the bed bugs. Then I bought some natural spray which seemed to have worked but unfortunately, the effect was short-term and the bed bugs came back.

SMITH  •  Tuesday, 10 May 2016 20:06

What amount of bed bug spray by Eco Defense is required to treat one room?

i_am  •  Saturday, 30 July 2016 19:03

If we take a standard size capacity of 16-oz, then, according to my experience, one bottle is more than enough for one room. This includes the treatment of the bed, carpet, furniture, etc., and there’ll still be some left over. The larger the room - the more you need – take two bottles or one with a larger volume.